Benzofuro [2, 3- b] benzofurans and benzofuro [3, 2 - b] benzofurans from 2 - hydroxyacetophenones. oligonucleotide synthesis.

R B Bates, S Caldera, B L Malik, S K Paknikar


Yamamura's modification of the Clemmensen reduction provided a one-step route to symmetrical benzofuro[2,3- b ]benzofurans and benzofuro[3,2-b ]benzofurans from Mehta and Uma (Tetrahedron Lett., 1996, 37, 1897-1898) using nitrogen oxides, served as the key step in the stereoselective syntheses of furanoid sugar amino acids.(I) leading to a novel methodology to the synthesis of a,a' -trans-dialkyl cyclic ethers (8). Keywords: Photosensitized electron transfer (PET), episelenonium radical cation, oxyselenylation, a,a' -trans-dialkyl cyclic ethers.been subjected to some kind of chemical or biological examination; thus vast majority of natural wealth remains unexplored. Studies on marine natural products initiated only recently have yielded molecules with exotic molecular architecture and diverse bioactivity. Well-directed research on natural products will enrich our bioresource base. In the current millennium, India is in a pre-eminent position to contribute towards natural product research with the utilization of its rich knowledge base and biodiversity.


Acetophenones; benzofurans.ylide.biocatalytic synthesis; chemical ecology; bioremedia- tion.

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